Genetically enhanced and implanted with synthetic wires under unrevealed circumstances, Wyre served as master assassin to the insurrectionist
Secret Empire roughly 15 years ago. His enhanced DNA was used to create the Breed, a group of savage warriors with enhanced feral abilities. Wyre proudly trained the Breed until realizing the horror they were becoming, at which point he slaughtered the Breed, demolished the facility and set out to slay those who escaped. Wyre also encountered
Weapon X agents such as
Garrison Kane and
Wolverine. One of the surviving Breed went on to become Alpha Flight's
Wild Child (later Weapon Omega). Wyre targeted Weapon Omega, the last Breed survivor in recent years, but was ultimately convinced of Omega's humanity and abandoned his quest. After escaping imprisonment, Wyre - rather than fleeing - saved Alpha trainee Manikin from the anti-vigilante Hardliners while the rest of
Alpha Flight was away, and he was granted freedom. Seeking redemption, Wyre aided Alpha Flight against a demonized
Witchfire, then joined them against the demon Carcass, another assault by the Hardliners, and the Master of the World and his
Omega Flight. Wyre's whereabouts following Alpha Flight's disbanding by the Canadian government are unrevealed.