After the life-changing events of SPIDER-GEDDON, Gwen Stacy of Earth-65 has resolved to stay on her home turf and resume her normally scheduled super-heroics as GHOST-SPIDER. But in the wake of the Hand's downfall, SOMETHING sinister has begun stalking the streets of New York at night. Will Gwen be able to track down the thing that goes bump in the dark, or will she become one more victim of the MAN-WOLF?!